Staphylococcus aureus: The impact on surgical site infections.

Surgical site infections – impact of staphylococcus aureus

Surgical site infections (SSIs) are a common complication of surgery, often resulting in very serious consequences. In addition to causing distress for patients and their families, research indicates that patients with SSIs have an increased risk of mortality. 1

There are several factors that impact the development of SSIs. However, many of these infections worldwide are associated with a common germ called Staphylococcus aureus. And Canada is no different.

A recent study by the Canadian Nosocomial Infection Surveillance Program found that Staphylococcus aureus was the most common bacteria identified in patients who developed SSIs after hip and knee replacement operations. 2

Staphylococcus aureus: what you should know.

Investigators have found that 20 - 40% of us have Staphylococcus aureus in our nose or on our skin and we don’t even know it’s there. 3 This is often referred to as being colonized.

Studies have shown the risk of developing an SSI with Staphylococcus aureus increases if we have the germ present on us at the time of surgery. 4 

Did you know? In the United States, there are between 160,000 and 300,000 SSIs every year. The economic impact of these infections on healthcare delivery is significant with an estimated annual cost ranging from $4 to $10 billion dollars. 5

nasal decolonization to reduce surgical site infections

Prevention of staphylococcus aureus through decolonization.

Science has shown that easy and effective infection prevention strategies can be used to remove or suppress the growth of Staphylococcus aureus and decrease the risk of SSI.

Preoperative showers with an anti-bacterial soap to reduce bioburden and remove the germ from the skin are recommended along with the insertion of an anti-bacterial agent into the nostrils. 6 

Historically, an antibiotic ointment has been widely used to decolonize the nose. A recognized concern with this practice has been the development of antibiotic resistance7 and poor compliance with lengthy treatment protocols.  

3M has a long history of developing high quality and effective products that meet our customers’ needs and help reduce the risk of SSIs. This is no exception.

An innovative, simple solution - 3M™ SoluPrepTM Nasal Antiseptic.

With a proprietary formula that has broad spectrum antibacterial activity, with no resistance in vitro, the 3M™ SoluPrepTM Nasal Antiseptic is a strong option.

This is due to four key attributes of the product. 8

  1. Effective: A one-time application helps reduce the risk of surgical site infections when part of comprehensive preoperative protocol. It effectively reduces bacteria in the nares, including staphylococcus aureus by 99.5% and has no evidence of antimicrobial resistance.
  2. Persistent: The patented formula is designed to work within one hour and maintain at least 12 hours of persistence.
  3. Easy: The broad-spectrum, fast-acting antiseptic allows for wider application than selective treatment protocols, fitting easily into preoperative processes.
  4. Comfortable: The film-forming, patented formula is designed not to drip, does not contain alcohol and has demonstrated excellent acceptability when used on nasal tissue.

For a full decolonization solution that offers additional optimal protection against surgical site infections, consider the 3M™ SoluPrep™ Antiseptic Skin Cleanser Sponge (4% w/v chlorhexidine gluconate), 100.10 as well. It removes oil, dirt, and bacteria from the skin and helps reduce the risk of infection.

Here’s what you can expect from it:

  1. Shower sponge pre-impregnated with 4% chlorhexidine gluconate.
  2. Easy-to-use single unit dose package.

Learn more about 3M™ SoluPrepTM Nasal Antiseptic and 3M™ SoluPrep™ Antiseptic Skin Cleanser Sponge.

For more information about 3M™ SoluPrep™ Antiseptic Skin Cleanser Sponge, visit the 3M™ SoluPrepTM website.

References

1. Magill SS, Edwards JR, Bamberg W, et al. Multistate point prevalence survey of health care–associated infections. NEJM 2014;370(13):1198-1208. doi:10.1056/NEJMoa1306801.

2. Roth V, Mitchell R, Vaschon V, et al. Periprosthetic infection following primary hip and knee arthroplasty: the impact of limiting the postoperative surveillance period. Infect Control Hosp Epidemiol 2017; 38:2 147-53

3. Sivaraman K, Venkataraman N, Cole AM. Staphylococcus aureus nasal carriage and its contributing factors. Future Microbiol 2009; 4:999-1008.

4. Bode LG, Kluytmans JA,Wertheim HF, et al. Preventing surgical site infections in nasal carriers of Staphylococcus aureus. N Engl J Med. 2010;362 (1):9-17.

Schweizer M, Perencevich E, McDanel J, et al. Effectiveness of a bundled intervention of decolonization and prophylaxis to decrease Gram positive surgical site infections after cardiac or orthopedic surgery: systematic review and meta-analysis. BMJ. 2013;346:f2743.

5. Magill SS, Edwards JR, Bamberg W, et al. Multistate point prevalence survey of health care–associated infections. NEJM 2014;370(13):1198-1208. doi:10.1056/NEJMoa1306801.

6. Bode LG, Kluytmans JA,Wertheim HF, et al. Preventing surgical site infections in nasal carriers of Staphylococcus aureus. N Engl J Med. 2010;362 (1):9-17.

Schweizer M, Perencevich E, McDanel J, et al. Effectiveness of a bundled intervention of decolonization and prophylaxis to decrease Gram positive surgical site infections after cardiac or orthopedic surgery: systematic review and meta-analysis. BMJ. 2013;346:f2743.

7. Poovelikunnel T, Gethin G, Humphreys H. Mupirocin resistance: clinical implications and potential alternatives for the eradication of MRSA. J Antimicrob Chemother. 2015;70:2681-92. Desroches M, Potier J, Laurent F, Bourrel AS, Doucet-Populaire F, Decousser JW. Prevalence of mupirocin resistance among invasive coagulase-negative staphylococci and methicillin-resistant Staphylococcus aureus (MRSA) in France: emergence of a mupirocin-resistant MRSA clone harbouring mupA. J Antimicrob Chemother. 2013;68:1714-7.

8. Data on file.

About the Author

Kathy McGhie

[enBio=Kathy is an award-winning expert in infection prevention and control. With more than 40 years of healthcare experience, Kathy has held multiple leadership positions in hospitals, and on the International Certification Board of Infection Control. Her expertise on the subject has also been published in articles she’s co-authored for several respected academic journals.],[enJob=Clinical and Technical Specialist, 3M Canada],[frBio=Kathy est une experte primée en prévention et contrôle des infections. Forte de plus de 40 ans d’expérience dans le domaine de la santé, Kathy a occupé de nombreux postes de direction dans des hôpitaux ainsi qu’au sein de l’International Certification Board of Infection Control. Elle a également fait part de son savoir-faire en la matière dans des articles rédigés en collaboration et publiés dans diverses revues universitaires respectées.],[frJob=Spécialiste clinique et technique, Compagnie 3M Canada]

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